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iwAL 2023 Session I: Clonal hematopoiesis in AML, early detection and potential therapeutics

VJHemOnc Podcast

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Introduction

This chapter discusses the use of CRISPR engineering in hematopoietic stem cells to investigate mutations and potential therapeutic vulnerabilities in clonal hematopoiesis in AML, with a focus on IDH1 mutant cases and the effects of specific inhibitors.

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