The Negative Effects of Saponins on the Gut

Have you been led to believe that oatmeal is good for you? This podcast is for you! Paul does a deep dive on why you may want to cut oats (and chocolate, and leafy greens) out for good for reasons like heavy metal accumulation, antinutrients, and defense chemicals.

00:07:30 The problem with grains

00:11:45 Heavy metals in oats, greens, chocolate and fish

00:20:00 How saponins damage the gut

00:31:30 Cadmium and heavy metals in oats, vegetables and chocolate 

00:48:15 Phytic acid

00:49:20 Pesticides in your oats

00:50:50 Mold contamination in grains

00:53:00 Takeaways on oats

References:

Influence of saponins on gut permeability and active nutrient transport in vitro: https://www.semanticscholar.org/paper/Influence-of-saponins-on-gut-permeability-and-in-Johnson-Gee/b100e152961fa3beb84c676ac0ae43e74b52af9e

Reducing the damage of quinoa saponins on human gastric mucosal cells by a heating process: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977518/

Triterpenoid Saponins in Oat Bran and Their Levels in Commercial Oat Products: https://figshare.com/collections/Triterpenoid_Saponins_in_Oat_Bran_and_Their_Levels_in_Commercial_Oat_Products/5002223

The biological action of saponins in animal systems: a review: https://pubmed.ncbi.nlm.nih.gov/12493081/

Effect of oat saponins and different types of dietary fibre on the digestion of carbohydrates: https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/effect-of-oat-saponins-and-different-types-of-dietary-fibre-on-the-digestion-of-carbohydrates/95992869AEC98CFAB161548C043F93E7

Effects of saponins and glycoalkaloids on the permeability and viability of mammalian intestinal cells and on the integrity of tissue preparations in vitro: https://pubmed.ncbi.nlm.nih.gov/20650190/

A major gene for grain cadmium accumulation in oat (Avena sativa L.): https://www.researchgate.net/publication/6204970_A_major_gene_for_grain_cadmium_accumulation_in_oat_Avena_sativa_L

Toxicity of cadmium and its health risks from leafy vegetable consumption:https://www.researchgate.net/publication/313975727_Toxicity_of_cadmium_and_its_health_risks_from_leafy_vegetable_consumption

Ideal Cereals With Lower Arsenic and Cadmium by Accurately Enhancing Vacuolar Sequestration Capacity: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467212/

Cadmium Levels in Soils and Crops in the United States: https://www.semanticscholar.org/paper/Cadmium-Levels-in-Soils-and-Crops-in-the-United-Chang-El-Amamy/18c4415de7340ae4b30ac9516c1acae4c4ed6300

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