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Ep. 30: “Comparative Immunology and Sharks” Featuring Dr. Hanover Matz

The Immunology Podcast

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Shark Immunology Uncovered

This chapter explores the distinct aspects of the immune systems of sharks compared to zebrafish and mammals, highlighting their unique lymphoid tissue organization and adaptive immune responses. It delves into the evolutionary significance of immunoglobulin genes and T cell subsets, examining how sharks' immune mechanisms are tailored for their ecological needs. The discussion also touches on the potential medical applications of shark-derived antibodies and the balance between the advantages and risks of their complex immune systems.

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