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Why does B12 damaged by nitrous oxide require megadosed folic acid rather than normal levels of folate? | Masterjohn Q&A Files #265

Mastering Nutrition

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The Effects of Sublingual Vitamin B12 on the Lermate Phenomenon

Patient serology had 42 homocysteine, that's massive. Folic acid was several times the top of the reference range. Four days later he started experiencing the lermate phenomenon which he described as a powerful tingling vibration. The phenomenon was also elicited by elevating his arms and problem. No worthy as mood and mental fogginess has improved. Is irritability dissipated as mental clarity normalized? All right. So I spend enough time on this. It seems possible that the B12 would up-regulate the methylation reactions and even though it should be freeing up the folate, it's actually by turning up the volume on the methylation that's

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