The Role of the Jack 2 Mutation in Polycythemia Vera

The Jack 2 mutation occurs in people, many of us as a conohomata-poecis lesion. In polycythemia vera, it really is central to the cause of the disease. And at this point, P. vera is defined now by the presence of a Jack 2 mutation either v617F or some of the less common Jack 2 mutations.