The Curbsiders Internal Medicine Podcast cover image

REBOOT #146 Pain Meds in CKD

The Curbsiders Internal Medicine Podcast

00:00

Tramadall

Tramadall is advertised as having two mechanisms of action. It's got a bivinacent al ight and it's also perceived as a mild opiote. The conversion of the s n or i parent compound, tram at all, to its metabolite is accomplished by an enzim in a liver. We have wildly varying levels of that ensime. Some of us have none, we won't make any opiod. And some of us have several copies of the gen that in codes for two, ty six, will turn tramadall into m one like nobody's business.

Transcript
Play full episode

The AI-powered Podcast Player

Save insights by tapping your headphones, chat with episodes, discover the best highlights - and more!
App store bannerPlay store banner
Get the app