80,000 Hours Podcast cover image

Rob Wiblin on self-improvement and research ethics

80,000 Hours Podcast

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Ethics of Challenge Trials in Vaccine Development

This chapter explores the ethical dilemmas surrounding human challenge trials in the context of COVID-19 vaccine testing. It contrasts the urgency of vaccine development with the moral implications of exposing healthy individuals to the virus, while also examining the regulatory challenges that hinder timely research. The discussion highlights the misalignment of incentives between policymakers and public interests, particularly regarding institutional review boards and their impact on valuable studies.

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