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65 - Taking Things to Heart
The Curious Clinicians
Rheumatic Heart Disease - What's the Mechanism?
Rheumatic fever in some way causes valvular damage, mitral more than aortic. There can be molecular mimicry between heart valves and antigens on strep pyogenes. antibodies that targeted the streptococcal M protein also strongly reacted against cardiac myosin molecules. This episode is sponsored by BetterHelp.
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