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PREPARE II Trial Result Presentation
Critical Care Reviews Podcast
The Importance of Fluid Bolus in Emergency Treatment
It was very challenging just to deliver this volume of fluid during this very emergent procedure. The effect estimate favored the no-fluid bolus group, and it's very unlikely that the enrollment of more patients would have revealed a benefit from fluid. So I think together this is pretty convincing evidence that we should not be routinely administering fluid bolus to prevent cardiovascular collapse.
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