Is There a Therapeutic Gene for Seizures?

In the DNA you have something called a promoter and the promoter is what tells a cell to produce that protein or not. What we've decided to do was to use a promoter which has a special property that it can detect whether the cell is overactive. So when a seizure happens this promoter switches itself on and that then leads the production of the protein. The protein then reduces the firing of those brain cells. We tested this in mice which were spontaneously epileptic and then we verified that the treatment would indeed suppress the seizures. In other mice the seizures were reduced in frequency without any deleterious side effects.