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7min chapter
Introduction to HLH
Investigating HLH
Mechanisms of Hemophagocytic Lymphohistiocytosis (HLH)
The chapter explores how HLH, a disease characterized by immune dysregulation, results in excessive immune activation and cytokine production leading to hyperinflammation. It discusses the role of key cytokines like interferon gamma, IL-1, IL-6, and TNF-alpha in the pathogenesis of HLH and its severe clinical manifestations.
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Listen to the best highlights from the podcasts you love and dive into the full episode