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#33 - Rudy Leibel, M.D.: Finding the obesity gene and discovering leptin

The Peter Attia Drive

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The Obe Mouse and the Diabedes Mouse

Ob mice and diabedes mice looked a great deal like each other, at least in terms of the over eating and the low energy expenditure. One was prone to get diabedes and the other not. Coleman showed that if you hooked an o b mouse up to a wild type mouse in this way, that the o b mouse would correct its hyper phagie,. Its excess food and take and actually begin to lose weight.

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