BBC Inside Science cover image

Seasonal Variation in Immunity, Chemosynthesis, Role of the ISS, Storing Digital Data in DNA

BBC Inside Science

00:00

The Seasonal Immune Response in the UK

We've observed for the very first time that the activity of the immune system changes from summer to winter and then back to summer again. So how did you unravel this seasonal immune response? I mean, it started off as a small experiment and you ended up sampling over 16,000 people all over the world. A third year student in my lab, Shack Castro, he'd been reading some fascinating literature about 24 hour circadian rhythms in mice,. In particular a gene called B-MAL1 in mice. And if you disrupt that gene, you completely disrupt the circadian rhythm of the mice, but you also disrupt the immune system and the mice become highly prone to inflammation.

Play episode from 02:03
Transcript

The AI-powered Podcast Player

Save insights by tapping your headphones, chat with episodes, discover the best highlights - and more!
App store bannerPlay store banner
Get the app