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NEJM This Week — September 18, 2025

NEJM This Week

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New Oncology and Metabolic Therapies

Randomized evidence that low‑dose aspirin lowers recurrence in PI3K‑altered colorectal cancer, plus trials of oral small‑molecule GLP‑1 (orforglipron) and 25 mg oral semaglutide for weight loss and glycemic control.

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