The Role of Estrogen in Menopause

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The canary in the coal mine as a woman is getting close to menopause from a biochemical standpoint is a rising FSH during that phase. If FSH starts to climb, especially if estradiol is low, you can be pretty sure that she's heading towards menopause. The purpose of luteinizing hormone is to prepare the endometrium for this implantation. And by about day 21, when progesterone peaks, the body figures out if it's pregnant or not.

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In this special episode of The Drive, Peter provides a comprehensive overview of the various endocrine systems: the thyroid system, the adrenal system, and the sex hormone system (for both men and women). He walks through the basic biology and the feedback cycles that regulate the production of these hormones and discusses the various options for the treatment of hormone deficiencies. In addition, Peter delves into hormone replacement therapy (HRT), providing nuanced insights into its appropriate usage and the clinical approach he adopts when working with patients.

Peter supplements these explanations with whiteboard illustrations. For a more complete understanding, we highly recommend watching these videos over just listening. The videos can be found on our YouTube channel or on the show notes page.

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