The ketogenic diet is actually used clinically for seizures. Ray Adderley was funded by the office of navy research to understand cellular and molecular mechanisms of central nervous system, oxygen toxicity which manifest the seizures. He found that when you move these things to animal models or humans, they don't work. But what we did in this study is administer a key tone ester at starvation level, which produced an increase in seizure latency from 15 minutes to 20 minutes. It's basically like a super rat. Prior work had been done showing that if you fast animals for 36 hours it will delay oxygen about 200 to 300 per cent. If you look like human blood on the animal, then pull out the
Dr. Dominic D’Agostino is a tenured Associate Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine. He is also a Research Scientist at the Institute for Human and Machine Cognition (IHMC). His laboratory develops and tests metabolic-based strategies for targeting CNS oxygen toxicity (seizures), epilepsy, neurodegenerative diseases, brain cancer and metastatic cancer.