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SGEM#468: Wide Open Monocytes – Using MDW to Diagnose Sepsis

The Skeptics Guide to Emergency Medicine

CHAPTER

Monocyte Distribution Width: A Sepsis Biomarker

This chapter explores the potential of monocyte distribution width (MDW) as a rapid biomarker for early sepsis detection in emergency settings. It includes a systematic review of its diagnostic accuracy against traditional clinical criteria, examining the transition from the sepsis 2 to the sepsis 3 framework. The discussion critiques research methodologies and highlights concerns regarding variability and biases in the study findings.

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