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Ep. 94: “Engineering Immunity” Featuring Dr. Lili Yang

The Immunology Podcast

CHAPTER

Engineering Immune Protection for Beta Cells

This chapter explores a groundbreaking genetic engineering strategy aimed at enhancing the immune survival of stem cell-derived beta cells, crucial for treating type 1 diabetes. The discussion includes the use of chimeric antigen receptor regulatory T cells and their role in protecting these cells from immune rejection. Additionally, the chapter examines the complex interactions between innate and adaptive immunity, particularly focusing on B cell functions and the implications of endogenous retroviruses in the immune response.

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