TWiV 1179: Dark matter and warning signs
This Week in Virology
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Biomarkers in Viral Infections
This chapter explores a challenging study investigating biomarkers for early and late phases of respiratory viral infections, particularly focusing on certain interferon-stimulated genes like IFI27 and MX1. It discusses the implications of using these biomarkers for improved diagnostic testing and the ethical concerns regarding the study's design and participant selection. The chapter also highlights the methodologies used in the study, including RNA sequencing and the risks associated with human challenge trials.
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