Optimizing Treatment Sequencing in Metastatic Triple-Negative Breast Cancer

The chapter delves into the sequencing of treatments for metastatic triple-negative breast cancer patients, comparing the benefits of Sacetuzumab over other chemotherapy options and discussing the challenges in using immunotherapy post-progression. It highlights a study showing promising responses to a specific treatment in patients with high TMB and touches on individual cases illustrating varied outcomes with immunotherapy treatments. The chapter also addresses the complexities of selecting appropriate therapies considering patient characteristics and potential complications, such as interstitial lung disease.