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Chemists can now precisely edit a molecule by deleting, adding or swapping single atoms in its core. This sort of molecular surgery could dramatically speed up drug discovery and might altogether revolutionize how organic chemists design molecules. In the past two years, more than 100 papers on the technique known as skeletal editing have been published.

In the past two years, there has been an explosion in the number of papers published relating to 'skeletal editing', a technique that allows chemists to precisely edit a molecule by deleting, adding or swapping single atoms in its core.

Although many of these methods are early in development, researchers hope skeletal editing could revolutionize how organic chemists design molecules, dramatically speeding up the drug-discovery process.

This is an audio version of our Feature: ‘Almost magical’: chemists can now move single atoms in and out of a molecule’s core

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