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February 2024

RCEM Learning

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De-labeling Patients with Penicillin Allergies and the Penfast Score

The chapter delves into the importance of de-labeling patients with penicillin allergies and introduces the penfast score as a clinical decision rule for direct oral challenge. It discusses the process of de-labeling, referral to allergy clinics, and the trial results highlighting the feasibility and equivalence of different testing approaches. The conversation also touches on managing penicillin allergies in emergency departments and the implications of using levofloxacin in patients labeled with penicillin allergy.

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