12min chapter

VJHemOnc Podcast cover image

BPDCN treatment and management: CD123-targeting agents, CNS involvement & approaching pediatric/AYA patients

VJHemOnc Podcast

CHAPTER

Targeting CD123 in BPDCN Treatment

This chapter delves into the significance of CD123 in BPDCN and the development of targeted therapies like diphtheria toxin conjugated interleukin 3. It explores successful clinical trials, approval of CD123-targeting agents, and ongoing advancements like the P-BAC antibody-drug conjugate and CAR T trials for potential future treatments.

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