2min chapter

Lex Fridman Podcast cover image

#133 – Manolis Kellis: Biology of Disease

Lex Fridman Podcast

CHAPTER

RNA Profiling and Epigenome Profiling for Alzheimer's Disease

In one year, we basically generated 10 million cells from human brain across a dozen different disorders. And when you look at the average, it washes out some potentially important signal that corresponds to ultimately the disease. We can now look at correlated activity across 2.3 million enhancers and 20,000 genes in each of millions of cells. This is piecing together the regulatory circuitry of every single type of neuron,. Every single type of astrocytes, oligodendrocyte, microglial cell inside the brains of 1,500 individuals.

00:00

Get the Snipd
podcast app

Unlock the knowledge in podcasts with the podcast player of the future.
App store bannerPlay store banner

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode

Save any
moment

Hear something you like? Tap your headphones to save it with AI-generated key takeaways

Share
& Export

Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode