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New lasso-shaped antibiotic kills drug-resistant bacteria

Nature Podcast

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Lariocidin: A New Hope Against Antibiotic Resistance

This chapter explores the urgent need for new antibiotics due to rising bacterial resistance and highlights the discovery of lariocidin, a promising new lasso-shaped peptide. Researchers discuss its unique mechanism of action, targeting the bacterial ribosome and demonstrating broad-spectrum effectiveness against resistant pathogens. The chapter also addresses challenges in developing lariocidin into a viable drug, while emphasizing its potential to combat drug-resistant infections.

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