2min chapter

The Immunology Podcast cover image

Ep. 35: “Inflammatory Bowel Disease” Featuring Dr. Karen Edelblum

The Immunology Podcast

CHAPTER

The Role of TGF-Pera in CD8 Tissue Residency

RONX3 highly expressed particularly on CD8 resident memory cells. If you knock out RONX3 using CRISPR, that this dramatically reduces the residency of CD8 cells and not so much of CD4 cells. A big part of this reprogramming has to do with increasing the accessibility to genes that respond to TGF-pera signaling. By doing this, TGF-Pera can drive a lot of what I mentioned are the genes that are associated with CD8 tissue residency,.

00:00

Get the Snipd
podcast app

Unlock the knowledge in podcasts with the podcast player of the future.
App store bannerPlay store banner

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode

Save any
moment

Hear something you like? Tap your headphones to save it with AI-generated key takeaways

Share
& Export

Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode