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#274 – Karl Deisseroth: Depression, Schizophrenia, and Psychiatry
Lex Fridman Podcast
Detecting That Things Are Pretty Bad Out There
All animals that have been studied in one form or another show this, even the worm that I mentioned earlier, C. elegans with 302 neurons, it can effectively give up in challenging situations. But then if you stimulate a couple very specific brain regions in particular ways, you can motivate them to overcome the challenge. So this is an ancestral conserved pattern to detect that things are pretty bad out there and to conserve energy, to hunker down, to wait out the storm. It seems like it doesn't make sense, right? And here's where we came from as the human family is kind of interesting.
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