Greg Jenner is joined by Dr Caroline Dodds Pennock and comedian Desiree Burch in the 15th century to learn all about the Columbian Exchange, which is often described as the start of globalisation. We go beyond the expeditions of Christopher Columbus to share the bigger story of a monumental exchange of plants, foods, animals, materials, people and culture across the continents. It’s also a life lesson on why you shouldn't set sail with a couple of cougars aboard your ship!

Research by Roxy Moore Written by Emma Nagouse and Greg Jenner Produced by Emma Nagouse and Greg Jenner Assistant Producer: Emmie Rose Price-Goodfellow Project Management: Isla Matthews Audio Producer: Steve Hankey

You’re Dead To Me is a production by The Athletic for BBC Radio 4.