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Immune 65: Infection infidelities with Jonathan Kagan

Immune

00:00

Viruses

Jonathan Gruber: I would guess, Jonathan, that your infidelis are all genetically based. None of them have to do with putting the wrong amino acids in, and the car doesn't work as well. So if you're talking about caps, it's falling apart or whatever. It's because the sequence is wrong, which all originates with a bad polymerase error. The dynamic nature may be the sister of replication infidelities. You are effectively allowing yourself to be a bit promiscuous in order to survey the space that you're trying to live in. But going down to phage is a really nice thing.

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