A lot of people with chronic pain get depressed because they think, oh God, another day I'm just going to be miserable. Part of the problem in dealing with chronic pain is that we tend to think of it as if it were acute pain. If you tell them not that you'll feel less pain, but whether you do or not, it won't bother you so much,. You reduce activity in the anterior cingulate cortex, which is part of the pain response network and the salience network also.

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