The Role of IV Fluids in Sepsis

In the restrictive group this happened within 21% of patients that did not have the four criteria for giving IV fluids. Urinary output was only an eligible reason within the first 24 hours or after randomisation. And again these were very, very pre-specified for the restrictive group. Whereas in the standard arm there seemed to be less mandated up of volume and presumably lower volume of use of IV or entrol fluids. So excellent retention to the primary end point so there's no problems with that.