TWiV 1187: The tau of herpesvirus
This Week in Virology
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Tau Phosphorylation and Viral Interactions in Alzheimer's Disease
This chapter examines the relationship between tau phosphorylation and herpes simplex virus (HSV-1) in the context of Alzheimer's disease. It highlights how HSV-1 infection increases tau phosphorylation in neurons and discusses the potential protective role of phosphorylated tau against neuronal death. Additionally, the chapter considers the implications of these findings for understanding both viral pathogenesis and neurodegeneration.
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