You could manipulate the genes of a mouse model. Again, either a knock-in or something similar. And then you have... Or knockout. The closest that you can get is this disease model, like a bowel cancer model in a mouse. That then you could not only try to experiment diagnostically, how better can we screen for pre-cancer states and even do what kind of environments. It's all genetic. So whether it may be inherited through a parent, or whether it's an environmental thing, like sun, chemical exposure, whatever,. All the effects are genetically based.