The Role of DTT in Blood Banks

DTT is one of my favorite, favorite blood bank tools because there's so many ways you can use this chemical. What it does is it, it, every time you, it sees a disulfide bond, it breaks it. So we can use DTT to destroy antigens that are on red cells. We would take a test red cell, treat it with DTT and any of the antigens or structures that rely on disulfide bonds for their confirmation like KEL system antigens. There's some other blood group system antigen, cartwright system antigings that require these disulfide Bonds to be intact for the antigen to be, have