Kant's Natural Worthlessness of Life

I was struck by, I just heard in your previous answer you mentioned one of the chapter titles, chapter four on Kant's genealogy of morality. That was the moment where the Nietzscheanism is poking through. And so right, the view is not that nature is worthless and we should chuck it, right? And just sort of construct whatever values we want, ex niello. But instead the worry and what motivates the worthlessness is the fact of Friedrich Nietzsche's irrationality. Such that if we were to live a natural existence ... both those lives are deeply dissatisfied to human beings for a variety of reasons.