The Role of Mutations in Protein Structures

Are we done with that protein? Is it like a totally understood system? And if not, what are the questions that still are driving you and your collaborator Dan? Yeah. So I would say one kind of really interesting thing that we found was not only do mutations have effects even really far away from the active site, but there's big clusters of these residues that all have a really similar impact. The next question is, is this, was, were we lucky in pathway with special in some way? Or are all really stable proteins have it? If you look at ones that are like path-based siblings, it's cousins, do they all have the same sort of, we call it