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What Causes Alzheimer's? Scientists Are Rethinking the Answer. (Pt 2)

The Quanta Podcast

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The Role of Genetics in Alzheimer's Disease

ApoE4 is the most significant genetic risk factor ever found for late onset Alzheimer's. People who have one copy of ApoE4 have a two to threefold elevated risk of developing Alzheimer's. The endosomal lysosomal system routinely starts to slow down and malfunction in aging cells, making these organelles into hot topics for longevity research.

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