Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast cover image

Episode 58: Medications For Neuraxial Anesthesia with Dave Berman and Anh Nguyen

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

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Basic Science of Local Anesthetics for Neuraxial Blockade

This chapter discusses the basic science behind local anesthetics for neuraxial blockade. It explains the structures, metabolism, pH and pKa values, lipid solubility, protein binding, and blockade effectiveness of local anesthetics. It also touches on the separation of motor and sensory block, the role of opioids in neuraxial anesthesia, and specific medications used in neuraxial anesthesia such as bupivacaine.

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