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#274 – Karl Deisseroth: Depression, Schizophrenia, and Psychiatry
Lex Fridman Podcast
The Importance of Optogenetics in Psychedelics
In theory, these are accessible with modern methods. Now that we have these rich recording methods, we can explore what are the precise millisecond resolution, cellular resolution, brain wide manifestations of these altered states. So like you could look at an altered state like on DMT, recorded across many people. And then from there, see where do these experiences originate in the brain in terms of single neurons? And then how do they propagate and interact with everything else? If there's some kind of common signal, like how do you narrow down the set of neurons that are responsible for a particular experience or for a particular behavioral effect? Here's where optogenetics is so useful because anytime you give an
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