Intro

Guest: Dr. Marius Wernig from Stanford University talks about his work with stem cells and his latest paper published in Science Translation on using iPCs to treat a serious skin disorder. Resources and Links How Brain Scans Can Diagnose Autism With 97% Accuracy - A much more objective measure—reading a person’s thoughts through an fMRI brain scan—might be able to diagnose autism with close to perfect accuracy. Mastodons Disappeared from Beringia before Ancient Humans Arrived – According to this article, new radiocarbon dates on American mastodon (Mammut americanum) fossils in Alaska and Yukon (eastern Beringia) suggest this species suffered local extinction tens of millennia before either human colonization. HIV’s Slower Progression to AIDS Caused by Certain Gene-Protein and ARV – Infected people with a gene that expresses a particular human leukocyte antigens (HLA) protein called HLA-B*57 progress more slowly to AIDS than usual. Radial Glia Require PDGFD–Pdgfrβ Signaling in Human but Not Mouse Neocortex – Researchers analyze differential gene co-expression relationships between the species, to demonstrate that the growth factor PDGFD is specifically expressed by Radial Glia in human, but not mouse, corticogenesis. Vegetable Oil Ingredient Key to Destroying Gastric Disease Bacteria – A group of researchers developed LipoLLA, a therapeutic nanoparticle that contains linolenic acid, which is a component in vegetable oils, to dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer in mice. Scientists Uncover Gene Associated with an Aggressive Breast Cancer – Scientists have identified a biomarker, a gene called RASAL2 that is strongly associated with triple negative breast cancer (TNBC), a highly aggressive carcinoma that often has early relapse and metastasis following chemotherapy. Star Trek-Like Invisible Shield Found Thousands of Miles Above Earth – Scientists have discovered an invisible shield roughly 7,200 miles above earth that blocks so-called "killer electrons," which can fry satellites and degrade space systems during intense solar storms. The Missing Gene that 'Triggers Autism': DNA Deficiency Linked to Being 'Unsociable And Disinterested in Others' – Scientists found mice deficient in a gene called neurexin-II showed similar symptoms to autism in humans, including a lack of sociability or interest in other mice. 'Lost' First Languages Leave Permanent Mark on the Brain, New Study Reveals – This article describes the study conducted to challenge the existing understanding that exposure to a language in the first year of a child’s life can be "erased" if he or she is moved to a different linguistic environment. Cystic Fibrosis Charity Sells Drug Rights to Pharma for $3.3 Billion – The Cystic Fibrosis (CF) Foundation has sold royalty rights to treatments developed with support from its ‘venture philantrophy’ model wherein the foundation provide upfront funding for pharmaceutical companies to help reduce the financial risk of developing drugs to treat CF. Genetic Testing for Personalized Nutrition Leads to Better Outcomes – Personalized dietary advice based on a person's genetic makeup improves eating habits compared to current "one-size-fits-all" dietary recommendations. Mental & Physical Pain May Be Different after All – A new study from the University of Colorado shows that physical and social pains actually use distinct neural circuits which may lead to specific treatment protocols for each pathway. Proposed Rules Will Vastly Expand Trove of Clinical Trial Data Reported in U.S. Database – This article describes the proposed rule that trial sponsors would need to report summary results for drugs and devices that are never approved—and not just for products that reach the market. Ontario Announces Funding for Stem Cell Institute – Ontario has announced funding for the creation of an institute for regenerative medicine and three 'disease challenge teams' to bridge the widening gap in the pro...