Many of the vasoconstricting effects of, let's say, the sympathetic nervous system and other certain drugs often work simply by triggering the release of endofellin. And you give that, you could give that when someone's having like an angina effect outcome. You give them a drug that induces nitric oxide. That dilates, particularly the coronary arteries. Well, blood gets in, more feeding. But yeah, nitric oxide, most potent vasodilator,. Endofellin, on the other hand, most potent Vasoconstrictor. More than angiotensin, too.