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Ep 180 Acetaminophen Poisoning – Pitfalls in Assessment and Management

Emergency Medicine Cases

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Is There a Delayed Infusion of NAC?

There's an anaphylactoid reaction documented with NAC, which means you get histamine release based on the speed of the infusion. If that patient came in at the 16-hour mark, you would start the NAC right away because time is liver. But if they come in at the four-hour mark,. you can afford to wait for that level to come back to decide whether or not they need to be treated. And we say this because we see patients that end up not requiring treatment and have given us a history where they say they took something.

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