Liver's Blood Supply and Drug Metabolism

Exploring the intricate circulatory system of the liver, including its dual afferent blood supply from the portal vein and hepatic artery, and how hepatic blood flow influences drug metabolism. The chapter dives into hepatic artery buffer response, adenosine regulation, and the impact of disease states on fluid dynamics, concluding with a discussion on drug clearance based on liver blood flow rates and zone-specific drug metabolism.