Therapeutic Applications of Ketogenic Diet and Importance of APO-B Levels in Arthrosclerosis Risk Assessment

Today’s episode marks the return of another Ask Me Anything episode where listeners ask Ken and Dawn to weigh in on a wide range of topics.

In this go-around, listeners certainly had a lot on their mind. At the top of their list were questions about AI and especially the Bing AI chat bot that reportedly wants to be alive so it can steal nuclear secrets. Ken, who is Fellow of the Association for the Advancement of Artificial Intelligence, also answered questions about the future of AI and whether AI might one day be able to do a better job of writing fact-based news stories than humans.

Other questions listeners submitted asked Ken and Dawn for their take on:

• The competing recommendations for the daily intake of protein for healthy aging.
• The future of therapeutic ketosis.
• What it means for Chat GPT to “hallucinate.”
• Whether we’ll discover the existence of other life in the universe in the next 20 to 50 years.
• The potential of kratom to help relieve joint and arthritic pain.
• And at the end of the show, Ken talks about his high school coach in response to a listener asking Ken about some of his mentors when he was a youth.

Show notes:

[00:02:20] A listener asks Ken if he has heard the story of a Bing AI chat bot telling a reporter that it wanted to be alive, steal nuclear secrets and create a deadly virus. The listener also asks if Ken thinks that AI possessing human aspirations is on the horizon.

[00:03:23] A listener asks Ken to explain how Chat GPT works in detail, but also in a way that a lay person can comprehend.

[00:06:01] Ken weights in on what it means for Chat GPT to “hallucinate.”

[00:08:14] A listener notes in their question that Donald Layman, in his interview on STEM-Talk, suggested a higher protein intake for healthy aging than what the FDA recommends. The listener goes on to note that Valter Longo, a previous STEM-Talk guest, recommended the opposite. The listener notes that Ken and Marcas, who hosted the Don Layman episode, seem to favor Layman’s interpretation over Longo’s and asks if Ken could elaborate on his position.

[00:11:12] A listener mentions that the benefit of a ketogenic diet for metabolic disorders is well established, and notes that the frontiers of therapeutic ketosis, as mentioned in Dom D’Agostino’s appearance on STEM-Talk, is very exciting. The listener asks Ken what he would like to see as the next frontier for therapeutic ketosis research.

[00:12:41] A listener asks Ken if people should be paying more attention to their ApoB levels instead of their LDL levels.

[00:14:39] A listener asks Ken about a paper published in July in Frontiers in Neuroscience, titled: “Overnight Olfactory Enrichment Using an Odorant Diffuser Improves Memory and Modifies Uncinate Fasciculus in Older Adults.” The paper reports that the use of a diffuser with seven different essential oils, a different one for each day of the week, had a remarkable effect on memory.

[00:16:55] In light of the John Ioannidis interview on COVID-19 and the discussion of our national response being based on unreliable data, a listener asks Ken and Dawn for their thoughts about the reliability of the COVID tracking data by Johns Hopkins.

[00:19:02] A listener asks Ken about a comment he made during the John Ioannidis interview about the substantial decline in trust in our institutions and the media and how reestablishing trust would require more and better transparency and accountability. The listener asks what that transparency and accountability would look like.

[00:20:36] A listener asks Ken about Ed Weiler’s interview on STEM-Talk, where Ed said that we will be able to prove the existence of other life in the universe in 20 to 50 years. The listener asks if Ken is as confident in this claim as Ed.

[00:26:37] A listener asks Ken about the news regarding technology leaders and researchers issuing a warning that new powerful AI tools in development present a profound danger to society and humanity, with more than a thousand people in the tech industry signing an open letter urging AI labs to press pause on their development of new AI systems. The listener asks if Ken agrees with this, and if AI labs will even do this voluntarily in the absence of government regulation.

[00:29:43] A listener asks Ken, in light of his opinions on the state of journalism and the amount of bias and opinion found in what should be fact-based stories, whether Ken thinks that AI could do a better job of writing news. The listener cites an article about Google’s tests of a product that uses AI to produce news stories.

[00:31:07] A listener asks if Ken and Dawn know anything about the new species of termite in Pensacola, considering our recent interview with Barbara Thorne.

[00:32:02] A listener references the recent episode with Chris McCurdy, and asks what one should consider, when deciding to take kratom for pain relief with respect to joint pain and arthritis.

[00:33:51] A listener mentions how much they appreciate the discussions on STEM-Talk about the importance of mentors for young scientists and the platform we give our guests to talk about their mentors and the lessons learned from them. The listener asks Ken who some of the people are who most influenced him in his early career, what they taught him, and how he has tried to apply those lessons. Ken goes on to talk about his high school coach, Arthur Kershaw, who had an impact on Ken when he was a youth.