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Parasitic Worm Infestation - The Co-Evolutionary Piece
In contrast to many other types of pathogens, parasitic worm infestation needs to last for a long time in one host. That's because after they've committed so much of developing into an adult form that's reproducing. They're relying upon their genetic material being passed out into the external environment undergoing development there and then being reintroduced to a new host.