The chapter dives into a journey of how one individual's interest in nanotechnology blossomed from studying physics to working with biological nanomachines. It explores the challenges and advancements in observing at the nanoscale using scanning probe microscopes and electron microscopes, enabling the visualization of DNA molecules and proteins. The conversation delves into merging biology, nanotechnology, and physics to gain insights into the emergence of life and its connection to ancient beliefs, touching on the historical separation of biology from physics and the impact of DNA discovery on genetics and societal perspectives.