Episode 17. Acquired Aplastic Anemia
Blood Cancer Talks
The Role of Eltrumbopag in TPO
I don't think anybody fully understands the mechanism of action of ultra trombopag specifically in a plastic media. Some people think that the stimulus to improve across all lineages is at the level of stem cells or even one step more mature progenitor cells, but it appears to sustain mato-plesis. So I kind of view it as something that must just buy time to hold and check the immune. And so it's like a double pump of response. You get a little extra pressure for reasons, probably at the stem cell, just to push through with mato-pleis from the ultra-mapag. Then the immunosuppression is given that time to
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