Weight Regain After GLP1s & Why It's Expected | Solo
The Dr. Tyna Show
L‑cell Suppression and Off‑ramp Strategies
Dr. Tyna details L-cell shutdown from high GLP-1 doses and the need to restore endogenous GLP-1 production.
EP. 244: In today’s episode, I break down the new BMJ study on weight regain after stopping GLP-1 medications and explain why these headlines do not mean GLP-1s are ineffective. Truth is, most people don’t realize how medication for a chronic disease works. I unpack what the research actually shows about obesity as a disease, treating vs. curing obesity, weight regain, metabolism, and why this outcome is expected when treating ANY chronic condition.
I also touch on why high-dose GLP-1 use without strength training, gut support, and sustainable lifestyle changes can create problems long term, and what a more thoughtful approach to metabolic health really looks like.
→ This Natural GLP-1 Stimulator Actually Works | Calocurb with Sarah Kennedy
→ Head to Calocurb.com/DRTYNA and use code DRTYNA for 10% off
Topics Discussed:
→ Why does weight regain happen after stopping GLP-1s?
→ Are GLP-1 medications meant to be taken long term?
→ Is microdosing GLP-1s effective for weight maintenance?
→ How do strength training and lifestyle affect GLP-1 results?
Sponsored By:
→ Puori | Go to https://puori.com/DRTYNA and use the code DRTYNA at checkout to get 32% off your first protein subscription order and get a free shaker worth $25.
→ BIOptimizers | BIOptimizers is having its New Year New You sale, and you may get up to 26% off select products, plus up to 45% off select bundles. Visit https://bioptimizers.com/drtyna and use code DRTYNA at checkout to get the best deal on Masszymes and all BIOptimizers products.
→ VivaRays | Go to https://VivaRays.com and use code DRTYNA for a special discount.
On This Episode We Cover:
→ 00:00:00 - Introduction
→ 00:00:50 - Chronic illness basics
→ 00:05:20 - Obesity and genetics
→ 00:12:59 - It's more than willpower
→ 00:15:21 - Weight loss statistics
→ 00:17:04 - Peptides, gut motility. And SIBO
→ 00:24:28 - Weight regain rate
→ 00:29:39 - Medication vs behavior
→ 00:34:09 - Limits of GLP-1s
→ 00:35:59 - Long term use
→ 00:39:36 - Treating obesity
→ 00:45:52 - Metabolic health
→ 00:49:20 - Solutions
→ 00:58:55 - GO TO THE GYM
Show Links:
→ Calocurb: Go to Calocurb.com/DRTYNA and use code DRTYNA for 10% off
→ Weighting on Methane: Weight Loss Medications Associated With Increased Incidence of SIBO
Further Listening:
→ EP. 212 | Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky
→ EP. 208 | This Natural GLP-1 Stimulator Actually Works | Calocurb with Sarah Kennedy
→ EP. 196 | The Answer Is The Gym | Quick + Dirty
Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.
The AI-powered Podcast Player
