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Human Genome Project - Nature’s editor-in-chief reflects 20 years on

Nature Podcast

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How Do Macrophages Trigger Stem Cells to Heal Injuries?

We wanted to see, could you just take nampt and add it into an injury sit and would that allow that injury to heal better? We did what we call a volumetric muscle last injury in a mouse leg. Then we introduced nap in a little gell like substance that allows namp to stay in the wound side. And then we went back ten days after looked o the injury, and we were really amazed was that at a certain dorse of net, which is not very high, the full muscle was completely regenerated. So this is kunof the first time that we've understood these macrophages being able to use the specific namped molecule to trigger the

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