3min chapter

Behind The Knife: The Surgery Podcast cover image

Doctor Cure Thyself: An Interview With Dr. David Fajgenbaum

Behind The Knife: The Surgery Podcast

CHAPTER

The M-Tor Signaling Pathway: A New Therapeutic Target for Castleman Disease

CDC developed the first ever diagnostic criteria and our patients get diagnosed a lot more quickly. We uncovered this M-Tor signaling pathway. It's the first therapeutic target to describe or discovered in 25 years. And so what's cool about M-Tor and also Jack is that there are these inhibitors that are developed for other things and they're at your pharmacy. So we've been treating patients off label with these drugs. But yeah, we're still working hard on that IL-6 block or end up getting FDA approval.

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